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Alterations in <t>corticospinal</t> coupling during force generation for ventral premotor cortex (PMV). Psycho-physiological interaction analysis between ipsilesional PMV ( A ) and the spinal cord and overview of the slices displayed along the z axis. B , Group comparison stroke (S) > control (C), controlled for maximum grip force. C , Patients with stroke: correlation with motor impairment, controlled for maximum grip force, age, side; ( Z maps were thresholded by Z >2.0 [group comparison] and | Z |>2.4 [correlation analysis], cluster significance threshold of P <0.05). Spinal cord activations are overlaid on the PAM50_t2-template, and Montreal Neurological Institute (MNI) coordinates are given. All images are in radiological orientation. The coupling strengths in spinal cluster voxels (MNI coordinates as indicated) were extracted and displayed in B and C . au indicates arbitrary units; NHP, Nine-Hole Peg Test; and UEFM, Fugl Meyer assessment of the upper extremity.
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Alterations in corticospinal coupling during force generation for ventral premotor cortex (PMV). Psycho-physiological interaction analysis between ipsilesional PMV ( A ) and the spinal cord and overview of the slices displayed along the z axis. B , Group comparison stroke (S) > control (C), controlled for maximum grip force. C , Patients with stroke: correlation with motor impairment, controlled for maximum grip force, age, side; ( Z maps were thresholded by Z >2.0 [group comparison] and | Z |>2.4 [correlation analysis], cluster significance threshold of P <0.05). Spinal cord activations are overlaid on the PAM50_t2-template, and Montreal Neurological Institute (MNI) coordinates are given. All images are in radiological orientation. The coupling strengths in spinal cluster voxels (MNI coordinates as indicated) were extracted and displayed in B and C . au indicates arbitrary units; NHP, Nine-Hole Peg Test; and UEFM, Fugl Meyer assessment of the upper extremity.

Journal: Stroke

Article Title: Altered Functional Connectivity Between Cortical Premotor Areas and the Spinal Cord in Chronic Stroke

doi: 10.1161/STROKEAHA.124.048384

Figure Lengend Snippet: Alterations in corticospinal coupling during force generation for ventral premotor cortex (PMV). Psycho-physiological interaction analysis between ipsilesional PMV ( A ) and the spinal cord and overview of the slices displayed along the z axis. B , Group comparison stroke (S) > control (C), controlled for maximum grip force. C , Patients with stroke: correlation with motor impairment, controlled for maximum grip force, age, side; ( Z maps were thresholded by Z >2.0 [group comparison] and | Z |>2.4 [correlation analysis], cluster significance threshold of P <0.05). Spinal cord activations are overlaid on the PAM50_t2-template, and Montreal Neurological Institute (MNI) coordinates are given. All images are in radiological orientation. The coupling strengths in spinal cluster voxels (MNI coordinates as indicated) were extracted and displayed in B and C . au indicates arbitrary units; NHP, Nine-Hole Peg Test; and UEFM, Fugl Meyer assessment of the upper extremity.

Article Snippet: In this cross-sectional study, patients with chronic stroke and healthy controls underwent corticospinal functional magnetic resonance imaging while performing a simple force generation task at the University Medical Center Hamburg-Eppendorf between September 2021 and June 2023.

Techniques: Comparison, Control

Alterations in corticospinal coupling during force generation for supplementary motor area (SMA). Psycho-physiological interaction (PPI) analysis between ipsilesional SMA ( A ) and the spinal cord and overview of the slices displayed along the z axis. B , Comparison control (C) >stroke (S), controlled for maximum grip force. C , Patients with stroke: correlation with motor impairment, controlled for maximum grip force, age, side; Z thresholds, and image presentations are identical to Figure 3 (exception: | Z |>1.9 for the correlation between PPI-SMA and Fugl Meyer assessment of the upper extremity [UEFM]). au indicates arbitrary units; and NHP, Nine-Hole Peg Test.

Journal: Stroke

Article Title: Altered Functional Connectivity Between Cortical Premotor Areas and the Spinal Cord in Chronic Stroke

doi: 10.1161/STROKEAHA.124.048384

Figure Lengend Snippet: Alterations in corticospinal coupling during force generation for supplementary motor area (SMA). Psycho-physiological interaction (PPI) analysis between ipsilesional SMA ( A ) and the spinal cord and overview of the slices displayed along the z axis. B , Comparison control (C) >stroke (S), controlled for maximum grip force. C , Patients with stroke: correlation with motor impairment, controlled for maximum grip force, age, side; Z thresholds, and image presentations are identical to Figure 3 (exception: | Z |>1.9 for the correlation between PPI-SMA and Fugl Meyer assessment of the upper extremity [UEFM]). au indicates arbitrary units; and NHP, Nine-Hole Peg Test.

Article Snippet: In this cross-sectional study, patients with chronic stroke and healthy controls underwent corticospinal functional magnetic resonance imaging while performing a simple force generation task at the University Medical Center Hamburg-Eppendorf between September 2021 and June 2023.

Techniques: Comparison, Control